Evaluation of Fluorescent Light Energy for the Treatment of Acute Second-degree Burns

ABSTRACT Introduction The use of photobiomodulation has been proposed to improve wound healing for the last two decades. Recent development in led a novel biophotonic platform that utilizes fluorescent light energy (FLE) within visible spectrum skin inflammation and wounds. Materials Methods In this article, FLE was used preliminary analysis on 18 case studies acute second-degree burns pilot study using an ex vivo human model. Efficacy tissue remodeling evaluated by monitoring improvements treated tissues, assessing pain patients, performing genome microarray FLE-treated samples. Results Healing reported all patients with without adverse effects or infections. Furthermore, model data suggest impacts different cellular pathways including essential immune-modulatory mechanisms. Conclusions results presented article are encouraging balances stages healing, which opens door initiating randomized controlled clinical trials establishing efficacy treatment phases burns.